Browsing by Author

The 0.1% of the population with glucokinase monogenic diabetes can be recognized by clinical characteristics in pregnancy: the Atlantic Diabetes in Pregnancy cohort.

Chakera, Ali J.; Spyer, G.; Vincent, N.; Ellard, Sian; Hattersley, Andrew T.; Dunne, F. P. (American Diabetes Association, 2014-02)

Identifying glucokinase monogenic diabetes (GCK-MODY) in pregnancy is important, as management is different from management for other forms of gestational diabetes mellitus (GDM) and there is no increased maternal risk of ...

1-year outcomes of the Xen45 glaucoma implant.

Smith, Michael; Charles, Roselin; Byles, Daniel (Nature, 2018-12-14)

To describe the 12-month outcomes of the Xen45 glaucoma stent.

10 Years of Improving Pain Assessment Documentation in a Foundation Trust Hospital

Murdoch, Julie; Price, Lucy; Cook, Laura; Wassall, Richard; Jackson, Mark (2016-09)

14 month old boy with abrupt-onset petechiae and bruising

Chanchlani, Neil (BMJ, 2019-06-05)

18F-FDG PET in the Diagnosis of Vascular Prosthetic Graft Infection: A Diagnostic Test Accuracy Meta-Analysis.

Rojoa, D.; Kontopodis, N.; Antoniou, Stavros A.; Ioannou, C. V.; Antoniou, G. A. (Elsevier, 2018-09-18)

For the diagnosis of vascular prosthetic graft infection (VPGI), an intra-operative peri-graft biopsy is often required. Controversy exists regarding the use of imaging techniques in the diagnostic process. This study aimed ...

2014 European thyroid association guidelines for the management of subclinical hypothyroidism in pregnancy and in children

Lazarus, J.; Brown, R. S.; Daumerie, C.; Hubalewska-Dydejczyk, A.; Negro, R.; Vaidya, Bijay (Karger, 2014-06-01)

This guideline has been produced as the official statement of the European Thyroid Association guideline committee. Subclinical hypothyroidism (SCH) in pregnancy is defined as a thyroid-stimulating hormone (TSH) level above ...

27 years of prenatal diagnosis for Huntington disease in the United Kingdom.

Turnpenny, Peter D. (Nature, 2018-12-14)

There is little long-term, population-based data on uptake of prenatal diagnosis for Huntington disease (HD), a late-onset autosomal dominant neurodegenerative disorder, and the effect of the availability of preimplantation ...

3-phase Technicium-99m bone scanning in patients with pain in the hip region after cemented total hip replacement: a multicentre series of 100 cases.

Hill, Daniel S; Naim, Soulat; Powell, Roy; Kinsella, Denis; Toms, Andrew; Howell, Jonathan (Wichtig, 2017-11-21)

The aim of this study was to assess the benefit of a Technetium-99M (HDP) 3-phase bone scan (TPBS) as an additional diagnostic test in the evaluation of pain in the hip region following cemented total hip replacement (THR) ...

5-hydroxymethylcytosine is highly dynamic across human fetal brain development.

Spiers, H.; Hannon, E.; Schalkwyk, L. C.; Bray, N. J.; Mill, Jonathan (BioMed Central, 2017-09-18)

Epigenetic processes play a key role in orchestrating transcriptional regulation during the development of the human central nervous system. We previously described dynamic changes in DNA methylation (5mC) occurring during ...

A 5-year randomized trial on the safety and efficacy of pimecrolimus in atopic dermatitis: a critical appraisal - comment.

Charman, Carolyn (Wiley, 2017-10)

50 years of total knee arthroplasty

Patel, Nimesh; Waterson, H B; Phillips, J R A (British Editorial Society of Bone & Joint Surgery, 2019-05)

A 60 year history of recurrent hypoglycaemia

Foteinopoulou, E.; Colclough, Kevin; Strachan, M. (BioScientifica, 2018-04-09)

8b.07: Results from the Uk Renal Denervation Affiliation- 246 Cases from 17 Centres

Sharp, Andrew; Hameed, A.; Nightingale, A.; Martin, U.; Mark, P.; McKane, W.; Cunnington, M.; Lobo, M.; Mahadevan, K.; Richardson, T.; Gerber, R.; ClifFord, Pete; Burchell, A.; Doulton, T.; Dimario, C.; Thackray, S.; Redwood, S.; Davies, J.; Antonios, T.; Dasgupta, I. (Wolters Kluwer, 2015-06)

OBJECTIVE: To describe the UK experience with Renal Denervation (RDN). DESIGN AND METHOD: RDN may lower blood pressure (BP) in people with resistant hypertension.The UK Renal Denervation Affiliation is an independent, ...

Abdominoperineal Excision: A Confusion in Terminology.

White, E S; Smart, Neil J.; Daniels, Ian R. (Wolters Kluwer, 2015-07)

Aberrant expression of the S1P regulating enzymes, SPHK1 and SGPL1, contributes to a migratory phenotype in OSCC mediated through S1PR2.

Patmanathan, S. N.; Johnson, Steven P.; Lai, Sook L.; Panja Bernam, S.; Lopes, V.; Wei, W.; Ibrahim, M. H.; Torta, F.; Narayanaswamy, P.; Wenk, M. R.; Herr, D. R.; Murray, P. G.; Yap, L. F.; Paterson, I. C. (Nature, 2016-05-10)

Oral squamous cell carcinoma (OSCC) is a lethal disease with a 5-year mortality rate of around 50%. Molecular targeted therapies are not in routine use and novel therapeutic targets are required. Our previous microarray ...

Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy.

James, N D; de Bono, J S; Spears, M R; Clarke, NW; Mason, M D; Dearnaley, D P; Ritchie, A W S; Amos, C L; Gilson, C; Jones, R J; Matheson, D; Millman, R; Attard, G; Chowdhury, S; Cross, W R; Gillessen, S; Parker, C C; Russell, J M; Berthold, D R; Brawley, C; Adab, F; Aung, San; Birtle, A J; Bowen, J; Brock, S; Chakraborti, P; Ferguson, C; Gale, J; Gray, E; Hingorani, M; Hoskin, P J; Lester, J F; Malik, Z I; McKinna, F; McPhail, N; Money-Kyrle, J; O'Sullivan, J; Parikh, O; Protheroe, A; Robinson, A; Srihari, N N; Thomas, C; Wagstaff, J; Wylie, J; Zarkar, A; Parmar, M K B; Sydes, M R (New England Journal of Medicine, 2017-07)

Abiraterone acetate plus prednisolone improves survival in men with relapsed prostate cancer. We assessed the effect of this combination in men starting long-term androgen-deprivation therapy (ADT), using a multigroup, ...