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A cost consequence study of the impact of a dermatology-trained practice nurse on the quality of life of primary care patients with eczema and psoriasis

Kernick, D.; Cox, A.; Powell, R.; Reinhold, D.; Sawkins, J.; Warin, A. (Royal College of General Practitioners, 2000-08-24)

BACKGROUND: The practice nurse is central to the development of a primary care-led National Health Service. Skin diseases can have a major impact on patients' lives but general practitioners (GPs) lack many of the skills ...

Healing at skin graft donor sites dressed with chitosan

Stone, C. A.; Wright, H.; Clarke, T.; Powell, R.; Devaraj, V. S. (Elsevier, 2000-09-23)

Chitosan is a derivative of chitin, extracted from the exoskeleton of lobsters, crabs and shrimps. As a semi-permeable biological dressing, it maintains a sterile wound exudate beneath a dry scab, preventing dehydration ...

beta-cell genes and diabetes: molecular and clinical characterization of mutations in transcription factors.

Frayling, Timothy M.; Evans, J. C.; Bulman, M. P.; Pearson, E. R.; Allen, Louisa; Owen, K.; Bingham, Coralie; Hannemann, Michael; Shepherd, Maggie; Ellard, Sian; Hattersley, Andrew T. (Highwire, 2001-02)

beta-Cell transcription factor genes are important in the pathophysiology of the beta-cell, with mutations in hepatocyte nuclear factor (HNF)-1alpha, HNF-4alpha, insulin promoter factor (IPF)-1, HNF-1beta, and NeuroD1/BETA2, ...

Home or surgery based screening for chronic obstructive pulmonary disease (COPD)?

Seamark, D. A.; Williams, S.; Timon, S.; Ward, A.; Ward, D.; Seamark, C.; Pinnuck, M.; Powell, R.; Halpin, D. M. G. (Nature Research, 2001-06-01)

AIMS: To compare the effectiveness of opportunistic spirometric screening of patients attending a general practice surgery with screening on randomly selected home visits. METHOD: 100 patients aged 45+ attending the Honiton ...

Treatment demands and differential treatment of patients with cystic fibrosis and their siblings: patient, parent and sibling accounts.

Foster, C.; Eiser, C.; Oades, Patrick; Sheldon, Christopher David; Tripp, J.H.; Goldman, P.; Rice, S.; Trott, J. (Wiley, 2001-07)

Cystic fibrosis (CF) is a progressive disease with no known cure. Advances in diagnosis and treatment have resulted in patients living longer and thus families live with the illness for longer. Treatments are becoming ...

Managing Spasticity in People With Multiple Sclerosis: A Goal-Oriented Approach to Intrathecal Baclofen Therapy

Jarrett, Louise; Leary, S. M.; Porter, B.; Richardson, D.; Rosso, T.; Powell, M.; Thompson, A. J. (Consortium of Multiple Sclerosis Centers, 2001-12)

The derivation and validation of an outcome predictive asthma score for use in general practice

Halpin, David; Powell, Roy; Dudbridge, S. B.; Stead, J.; Sweeney, K. (BMJ, 2001-12-01)

Improving foot care for people with diabetes mellitus--a randomized controlled trial of an integrated care approach

Donohoe, M. E.; Fletton, J. A.; Hook, A.; Powell, R.; Robinson, I.; Stead, J. W.; Sweeney, K.; Taylor, R.; Tooke, J. E. (Wiley, 2001-12-24)

AIMS: To evaluate a model of integrated diabetic footcare, for identification and clinical management of the high risk diabetic foot, centred on the primary care-based diabetic annual review. METHODS: A pragmatic randomized ...

The role of the nurse in the management of spasticity: care pathway

Jarrett, Louise (Multiple Sclerosis Trust, 2002)

Head lice infestation: bug busting vs. traditional treatment

Plastow, L.; Luthra, M.; Powell, R.; Wright, J.; Russell, D.; Marshall, M. N. (Wiley, 2002-02-02)

The two main methods of managing head lice infestation in the UK are head lice lotions and bug busting; there is no conclusive evidence as to which of these methods is most effective. The aim of this study was to compare ...

A pragmatic randomised controlled trial of an asthma nurse in general practice

Kernick, D.; Powell, R.; Reinhold, D. (Nature Research, 2002-03-01)

AIM: To measure the impact of a nurse led asthma clinic on the quality of life of patients with asthma. DESIGN: A randomised controlled trial with delayed intervention in the control group. OUTCOMES: Primary outcome measure: ...

Assessing communication skills of GP registrars: a comparison of patient and GP examiner ratings

Greco, M.; Spike, N.; Powell, R.; Brownlea, A. (Wiley, 2002-04-10)

CONTEXT: General practice. OBJECTIVES: To compare ratings of GP registrars' communication skills by patients and GP examiners. DESIGN: A comparative study where the communication skills of GP registrars were assessed both ...

Maturity-onset diabetes of the young caused by a balanced translocation where the 20q12 break point results in disruption upstream of the coding region of hepatocyte nuclear factor-4alpha (HNF4A) gene.

Gloyn, A. L.; Ellard, Sian; Shepherd, Maggie; Howell, R. T.; Parry, E. M.; Jefferson, A.; Levy, E. R.; Hattersley, Andrew T. (Highwire, 2002-07)

Monogenic human disorders have been used as paradigms for complex genetic disease and as tools for establishing important insights into mechanisms of gene regulation and transcriptional control. Maturity-onset diabetes of ...