Browsing by Title
Now showing items 1655-1674 of 1824
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Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: results from the initial screening round of the IMPACT study
(Elsevier, 2014-09-01)BACKGROUND: Men with germline breast cancer 1, early onset (BRCA1) or breast cancer 2, early onset (BRCA2) gene mutations have a higher risk of developing prostate cancer (PCa) than noncarriers. IMPACT (Identification of ... -
Targeting surface voids to counter membrane disorders in lipointoxication-related diseases.
(The Company of Biologists, 2016-06-15)Saturated fatty acids (SFA), which are abundant in the so-called western diet, have been shown to efficiently incorporate within membrane phospholipids and therefore impact on organelle integrity and function in many cell ... -
The Tatton-Brown-Rahman Syndrome: A clinical study of 55 individuals with de novo constitutive DNMT3A variants
(Wellcome, 2018-04)Tatton-Brown-Rahman syndrome (TBRS; OMIM 615879), also known as the DNMT3A-overgrowth syndrome, is an overgrowth intellectual disability syndrome first described in 2014 with a report of 13 individuals with constitutive ... -
Teaching classroom management ? a potential public health intervention?
(Emerald, 2015-06)The purpose of this paper is to explore the feasibility of a classroom management course as a public health intervention. Improved socio-emotional skills may boost children’s developmental and academic trajectory, while ... -
A technique to visualise the urethral meatus in difficult male catheterisations.
(Royal College of Surgeons, 2015-12-16) -
Temperature Spatially Offset Raman Spectroscopy (T-SORS): Subsurface Chemically Specific Measurement of Temperature in Turbid Media Using Anti-Stokes Spatially Offset Raman Spectroscopy.
(American Chemical Society, 2016-01-05)Here we propose and demonstrate a new analytical method for the noninvasive measurement of subsurface temperatures within diffusely scattering (turbid) media in combination with high chemical selectivity. The method is ... -
Ten years of the national genetic diabetes nurse network: a model for the translation of genetic information into clinical care
(Clinical Medicine, 2014-04-01)Increasing technological advances have resulted in the recognition of a range of genetic conditions not traditionally seen by clinical genetics teams. This has implications for the education of other healthcare professionals ... -
Tensioned fine wire for proximal femur traction table reduction in amputees.
(Royal College of Surgeons, 2016-08-11) -
Testing of a novel Valsalva Assist Device with supine and modified positions in healthy volunteers.
(BMJ, 2018-12-01)The Valsalva manoeuvre (VM) is used to treat supraventricular tachycardia (SVT) by inducing a vagal response (drop in HR). There is debate as to the best position in which to carry out the VM and how the strain should be ... -
Tests aiding diagnosis of monogenic diabetes
(Wiley, 2017-07-10) -
The therapeutic effect of rosuvastatin and propylthiouracil on ameliorating high-cholesterol diet-induced rabbit aortic atherosclerosis and stiffness.
(Elsevier, 2017-01-15)We tested the hypothesis that arteriosclerosis-augmented aortic pulse wave velocity (PWV) and -impaired vasorelaxation were attenuated by rosuvastatin (Rosu) and propylthiouracil (PTU) therapy. -
This house believes the NHS should be privatised - 1st southwest medical debate.
(BioMed Central, 2015-09-22)The inaugural southwest medical debate, between Exeter and Plymouth medical schools and respective health services, was held on the 3rd December 2014. Plymouth proposed the motion "This house believes the NHS should be ... -
Thoracodorsal or Internal Mammary Recipient Vessels for Microvascular Breast Reconstruction?
(Wolters Kluwer, 2012-05) -
Three Cases of Femoral Stem Failure in Rotating Hinge Revision Total Knee Arthroplasty: Causes and Surgical Considerations.
(Korean Orthopaedic Association, 2018-06)Catastrophic failure of stemmed components in arthroplasty is an uncommon but a serious complication. Stem fractures and techniques for addressing these have been described following hip arthroplasty but much less so ... -
Three cases of Wolfram syndrome with different clinical aspects.
(De Gruyter, 2015-03)Wolfram syndrome is an autosomal recessive disorder caused by mutations in the WFS1 gene. Clinical heterogeneity has been reported both within and between families with WFS1 mutations. -
Three-dimensional computed tomography reveals different donor-site deformities in adult and growing microtia patients despite total subperichondrial costal cartilage harvest and donor-site reconstruction.
(Wolters Kluwer, 2014-03)Donor-site deformity may complicate autologous costal cartilage harvest for microtia reconstruction. This is reportedly prevented by total subperichondrial costal cartilage harvest, costochondral growth center preservation, ... -
The 'three-legged stool': a system for spinal informed consent.
(British Editorial Society of Bone and Joint Journal, 2016-11)Many hospitals do not have a structured process of consent, the attainment of which can often be rather 'last-minute' and somewhat chaotic. This is a surprising state of affairs as spinal surgery is a high-risk surgical ... -
Thyroid research: stepping forward.
(BioMed Central, 2016-03-15)It is eight years since Thyroid Research was launched with an aim to enhance opportunities for scientists and clinicians, working in the rapidly advancing field of thyroidology, to publish their research (Thyroid Res 1(1):1, ...