Browsing by Title
Now showing items 408-427 of 1919
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Day case laparoscopic cholecystectomy: Safety and feasibility in obese patients.
(Elsevier, 2017-12-09)Day-case laparoscopic cholecystectomy (DCLC) is not universally adopted and its use is limited to patients selected by non-standardized criteria. Since laparoscopic cholecystectomy is considered technically more difficult ... -
A Deep Intronic HADH Splicing Mutation (c.636+471G>T) in a Congenital Hyperinsulinemic Hypoglycemia Case: Long Term Clinical Course.
(Galenos, 2015-06)Unlike other congenital fatty acid oxidation defects, short-chain L-3-hydroxyacyl-CoA (SCHAD, HADH) deficiency is characterised by hypoglycemia with hyperinsulinism in the neonatal or infancy periods. The long-term and ... -
Deep phenotyping of fourteen new patients with IQSEC2 variants, including monozygotic twins of discordant phenotype
(Wiley, 2019-01-21)Whole exome sequencing has established IQSEC2 as a neurodevelopmental disability gene. The IQSEC2 variant phenotype includes developmental delay, intellectual disability, epilepsy, hypotonia, autism, developmental regression, ... -
Defining a New Prognostic index for Stage I Non-seminomatous Germ Cell Tumors using CXCL12 Expression and Proportion of Embyronal Carcinoma
(Clinical Cancer Research, 2015-10-09)PURPOSE: Up to 50% of patients diagnosed with stage I non-seminomatous germ cell tumors (NSGCT) harbor occult metastases. Patients are managed by surveillance with chemotherapy at relapse or adjuvant treatment up-front. ... -
Defining drug response for stratified medicine.
(Elsevier, 2017-01)The premise for stratified medicine is that drug efficacy, drug safety, or both, vary between groups of patients, and biomarkers can be used to facilitate more targeted prescribing, with the aim of improving the benefit:risk ... -
Defining left ventricular remodeling following acute ST-segment elevation myocardial infarction using cardiovascular magnetic resonance.
(BioMed Central, 2017-03-13)The assessment of post-myocardial infarction (MI) left ventricular (LV) remodeling by cardiovascular magnetic resonance (CMR) currently uses criteria defined by echocardiography. Our aim was to provide CMR criteria for ... -
Defining the genetic aetiology of monogenic diabetes can improve treatment.
(Taylor & Francis, 2006-09)A molecular genetic diagnosis is now possible for > 80% of patients with monogenic diabetes. This not only provides accurate information regarding inheritance and prognosis, but can inform treatment decisions and improve ... -
Defining the role of common variation in the genomic and biological architecture of adult human height
(Nature, 2014-11)Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height. By testing different numbers of variants in ... -
Delayed absorbable synthetic plug (GORE BIO-A ) for the treatment of fistula in ano: a systematic review
(Wiley, 2016-01-04)AIM: Recent advances in the treatment of fistula-in-ano have focused on surgical techniques that preserve sphincter integrity. Plugs that obliterate the lumen of the fistula track have been proposed as one such method and ... -
Delineation of dominant and recessive forms of LZTR1-associated Noonan syndrome
(Wiley, 2019-06)Noonan syndrome (NS) is characterised by distinctive facial features, heart defects, variable degrees of intellectual disability and other phenotypic manifestations. Although the mode of inheritance is typically dominant, ... -
Delving Deep into the Proteome of Lung Fibrosis Brings Plasma Cells to the Surface.
(ATS Journals, 2017-07-11) -
Dental amalgam tattoo consequent to a human bite injury
(Elsevier, 2005-12) -
Depression in hospitalized elderly people
(MAG Online Library, 2014-08-01) -
Derivation and external validation of a case mix model for the standardized reporting of 30-day stroke mortality rates
(Stroke, 2014-11-01)BACKGROUND AND PURPOSE: Case mix adjustment is required to allow valid comparison of outcomes across care providers. However, there is a lack of externally validated models suitable for use in unselected stroke admissions. ... -
Dermatological postoperative patient information leaflets: is it time for more uniformity?
(Wiley, 2015-08-14)INTRODUCTION: Patient information leaflets (PILs) are an important source of information for patients postoperatively. There are currently no nationally agreed standards by dermatologists for postoperative advice following ... -
Description of the rates, trends and surgical burden associated with revision for prosthetic joint infection following primary and revision knee replacements in England and Wales: an analysis of the National Joint Registry for England, Wales, Northern Ireland and the Isle of Man.
(BMJ, 2017-07-10)To describe the prevalence rates of revision surgery for the treatment of prosthetic joint infection (PJI) for patients undergoing knee replacement, their time trends, the cumulative incidence function of revision for PJI ... -
The design and development of a complex multifactorial falls assessment intervention for falls prevention: The Prevention of Falls Injury Trial (PreFIT).
(BioMed Central, 2017-06-01)This paper describes the design and development of a complex multifactorial falls prevention (MFFP) intervention for implementation and testing within the framework of a large UK-based falls prevention randomised controlled ... -
Details of a Tendon–Sparing Posterior Approach in Hemiarthroplasty in the Treatment of Displaced Intracapsular Neck of Femur Fracture
(Journal of Arthritis, 2017-06-22)