Browsing by Title
Now showing items 2639-2658 of 3493
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Radiological progression of end colostomy trephine diameter and area
(BJS, 2018-10-24)Development of a parastomal hernia is common following abdominoperineal excision (APE). The true incidence is difficult to assess fully owing to differing lengths of follow-up and techniques used to assess herniation; ... -
Radiolucent triangle and U-bolster for lower leg positioning for circular frame application.
(Royal College of Surgeons, 2018-08-16) -
Radiotherapy for acute, high-grade spinal cord compression caused by vertebral haemangioma
(Elsevier, 2015-10-19) -
Radiotherapy to the primary tumour for newly diagnosed, metastatic prostate cancer (STAMPEDE): a randomised controlled phase 3 trial.
(Elsevier, 2018-10-18)Based on previous findings, we hypothesised that radiotherapy to the prostate would improve overall survival in men with metastatic prostate cancer, and that the benefit would be greatest in patients with a low metastatic ... -
Raising awareness of Graves' orbitopathy with early warning cards.
(Wiley, 2017-07-29)Clinically significant Graves' orbitopathy (GO) develops in about 25% of those with Graves' disease (GD); most cases of GD in the UK are managed by endocrinologists. Despite this, patients report significant delays before ... -
Raman spectroscopy and multivariate analysis for the non invasive diagnosis of clinically inconclusive vulval lichen sclerosus.
(Royal Society of Chemistry, 2016-11-09)Vulval lichen sclerosus (LS) is a common inflammatory condition associated with an increased risk of developing vulval carcinoma. Diagnosis is usually clinical although biopsy is necessary if the diagnosis is uncertain or ... -
Raman spectroscopy for rapid intra-operative margin analysis of surgically excised tumour specimens
(Royal Society of Chemistry, 2019-11)Raman spectroscopy, a form of vibrational spectroscopy, has the ability to provide sensitive and specific biochemical analysis of tissue. This review article provides an in-depth analysis of the suitability of different ... -
Random non-fasting C-peptide testing can identify patients with insulin-treated type 2 diabetes at high risk of hypoglycaemia.
(Springer, 2017-10-05)The aim of this study was to determine whether random non-fasting C-peptide (rCP) measurement can be used to assess hypoglycaemia risk in insulin-treated type 2 diabetes. -
Random non-fasting C-peptide: bringing robust assessment of endogenous insulin secretion to the clinic.
(Wiley, 2016-04-21)Measuring endogenous insulin secretion using C-peptide can assist diabetes management, but standard stimulation tests are impractical for clinical use. Random non-fasting C-peptide assessment would allow testing when a ... -
A Randomised Controlled Trial of Local Infiltration Analgesia Versus Femoral Nerve Block for Postoperative Analgesia Following Total Knee Arthroplasty
(PubMed Central, 2020-09-02)Background Total knee replacement is often associated with significant postoperative pain. Although the use of a femoral nerve block is well-established, local infiltration analgesia has gained popularity in recent years. ... -
Randomised controlled trial of the Limit of Detection of Troponin and ECG Discharge (LoDED) strategy versus usual care in adult patients with chest pain attending the emergency department: study protocol.
(BMJ, 2018-10-02)Observational data suggest a single high-sensitivity troponin blood test taken at emergency department (ED) presentation could be used to rule out major adverse cardiac events (MACE) in 10%-60% of ED patients with chest ... -
Randomised Evaluation of Modified Valsalva Effectiveness in Re-Entrant Tachycardias (REVERT)
(2015-11-05)The Valsalva manoeuvre is an internationally recommended physical emergency treatment for supraventricular tachycardia (SVT), an abnormal fast heart rhythm. However in normal practice, the manoeuvre only works in 5–20% of ... -
Randomised Evaluation of modified Valsalva Effectiveness in Re-entrant Tachycardias (REVERT) study
(BMJ, 2014-03-01)INTRODUCTION: The Valsalva manoeuvre (VM) is a recommended first-line physical treatment for patients with re-entrant supraventricular tachycardia (SVT), but is often ineffective in standard practice. A failed VM is typically ... -
A randomised trial of observational learning from 2D and 3D models in robotically assisted surgery
(Springer, 2018-05-14) -
A randomised, double-blind, parallel-group trial to assess mercaptopurine versus placebo to prevent or delay recurrence of Crohn’s disease following surgical resection (TOPPIC)
(NIHR, 2017-09)Crohn’s disease (CD) is a chronic, relapsing, inflammatory bowel disease. Up to 65% of patients with CD require an operation to control the disease within 10 years. Both endoscopic and clinical recurrence is common within ... -
Randomized clinical trial of DTaP5-HB-IPV-Hib vaccine administered concomitantly with meningococcal serogroup C conjugate vaccines during the primary infant series
(Elsevier Science, 2020-07-31)Background: Concomitant administration of vaccines simplifies delivery. DTaP5-HB-IPV-Hib is a fully liquid, combination vaccine against 6 diseases. This study evaluated the compatibility of DTaP5-HB-IPV-Hib with 2 different ... -
A randomized controlled trial of postoperative analgesia following total knee replacement: transdermal Fentanyl patches versus patient controlled analgesia (PCA).
(Springer, 2015-08)This randomized controlled trial compared a standard patient controlled analgesic (PCA) regime with a transdermal and oral Fentanyl regime for post-operative pain management in patients undergoing total knee replacement. -
A randomized trial comparing treatments for varicose veins
(NEJM, 2014-09-25)BACKGROUND: Ultrasound-guided foam sclerotherapy and endovenous laser ablation are widely used alternatives to surgery for the treatment of varicose veins, but their comparative effectiveness and safety remain uncertain. ... -
A Randomized Trial of the Optimum Duration of Acoustic Pulse Thrombolysis Procedure in Acute Intermediate-Risk Pulmonary Embolism: The OPTALYSE PE Trial.
(Elsevier, 2018-07-23)The aim of this study was to determine the lowest optimal tissue plasminogen activator (tPA) dose and delivery duration using ultrasound-facilitated catheter-directed thrombolysis (USCDT) for the treatment of acute ...