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Now showing items 3442-3461 of 3493
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Ward-based high-flow nasal cannula oxygen for acute lower respiratory tract infection.
(Mark Allen Group, 2021-05-02) -
Waterlow score as a surrogate marker for predicting adverse outcome in acute pancreatitis.
(Royal College of Surgeons, 2016-01)Introduction Introduced originally to stratify risk for developing decubitus ulcers, the Waterlow scoring system is recorded routinely for surgical admissions. It is a composite score, reflecting patients' general condition ... -
WDR26 Haploinsufficiency Causes a Recognizable Syndrome of Intellectual Disability, Seizures, Abnormal Gait, and Distinctive Facial Features.
(Cell Press, 2017-07-06)We report 15 individuals with de novo pathogenic variants in WDR26. Eleven of the individuals carry loss-of-function mutations, and four harbor missense substitutions. These 15 individuals comprise ten females and five ... -
The Weather and Ménière's Disease: A Longitudinal Analysis in the UK.
(LWW, 2016-11-17)Changes in the weather influence symptom severity in Ménière's disease (MD). -
Weekly dose-dense chemotherapy in first-line epithelial ovarian, fallopian tube, or primary peritoneal cancer treatment (ICON8): overall survival results from an open-label, randomised, controlled, phase 3 trial
(Elsevier, 2022-06-12)BACKGROUND: Standard-of-care first-line chemotherapy for epithelial ovarian cancer is carboplatin and paclitaxel administered once every 3 weeks. The JGOG 3016 trial reported significant improvement in progression-free and ... -
Weekly variation in health-care quality by day and time of admission: a nationwide, registry-based, prospective cohort study of acute stroke care.
(Elsevier, 2016-05-10)Studies in many health systems have shown evidence of poorer quality health care for patients admitted on weekends or overnight than for those admitted during the week (the so-called weekend effect). We postulated that ... -
Weight change and sulfonylurea therapy are related to 3 year change in microvascular function in people with type 2 diabetes
(Springer, 2020-06)Aims/hypothesis: Although cardiovascular disease is the biggest cause of death in people with diabetes, microvascular complications have a significant impact on quality of life and financial burden of the disease. Little ... -
What errors make a laparoscopic cancer surgery unsafe? An ad hoc analysis of competency assessment in the National Training Programme for laparoscopic colorectal surgery in England.
(Springer, 2016-03)The National Training Programme for laparoscopic colorectal surgery in England was implemented to ensure training was supervised, structured, safe and effective. Delegates were required to pass a competency assessment ... -
What influences the sustainability of an effective psychosocial intervention for people with dementia living in care homes? A 9 to 12‐month follow‐up of the perceptions of staff in care homes involved in the WHELD randomised controlled trail
(Wiley, 2019-05)The study aims to understand the factors that care home staff felt enabled or hindered them in continuing to use the well-being and health for people with dementia (WHELD) psychosocial approach in their care home and ... -
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(BMJ, 2017-04-10) -
What is known about the nutritional intake of women with Hyperemesis Gravidarum?: A scoping review.
(Elsevier, 2021-02-01)Hyperemesis gravidarum (HG) is characterised by extreme nausea and vomiting of pregnancy, which can lead to dehydration, weight loss and electrolyte disturbances. Historically research has been challenging due to a lack ... -
What is new in migraine management in children and young people?
(BMJ, 2022-02-21)For this narrative review, we found recent publications on the use and effectiveness of old therapies including nutraceuticals, such as riboflavin, vitamin D, magnesium, melatonin and talking therapies. Recent large trials ... -
What is the evidence for the use of biologic or biosynthetic meshes in abdominal wall reconstruction?
(Springer, 2018-01-31)Although many surgeons have adopted the use of biologic and biosynthetic meshes in complex abdominal wall hernia repair, others have questioned the use of these products. Criticism is addressed in several review articles ... -
What is the lived experience of anxiety for people with Parkinson's? A phenomenological study
(PLoS One, 2021-04-08)PURPOSE: Anxiety is a common non-motor symptom of Parkinson's and there is no specific pharmacological intervention for people with Parkinson's who experience anxiety. Yet there is little specific research documenting how ... -
What is the patient experience following revision knee replacement: A systematic review and meta-analysis of the medium term patient reported outcomes
(Elsevier, 2022-02-19)AIMS: Revision knee replacement is an increasingly common procedure, however, information on patient-focused outcomes is limited. This systematic review and meta-analysis aimed to investigate the medium-term patient reported ... -
What Next After Metformin in Type 2 Diabetes? Selecting the Right Drug for the Right Patient
(Springer, 2020-06)Introduction: Metformin is the recommended initial treatment in type 2 diabetes mellitus (T2DM), but when this does not give adequate glucose control the choice of which second-line drug to use is uncertain as none have ... -
What should be included in case report forms? Development and application of novel methods to inform surgical study design: a mixed methods case study in parastomal hernia prevention
(BMJ, 2022-10-05)OBJECTIVES: To describe the development and application of methods to optimise the design of case report forms (CRFs) for clinical studies evaluating surgical procedures, illustrated with an example of abdominal stoma ... -
What the HLA-I!-Classical and Non-classical HLA Class I and Their Potential Roles in Type 1 Diabetes
(Springer, 2019-12-09)Purpose of review: Hyperexpression of classical HLA class I (HLA-I) molecules in insulin-containing islets has become a widely accepted hallmark of type 1 diabetes pathology. In comparison, relatively little is known about ... -
What's in a smile? A review of the benefits of the clinician's smile
(BMJ, 2019-01-30)For millennia, the smile has been recognised as a powerful communication device, offering benefits to both giver and receiver with few drawbacks. A sign of compassion, empathy and friendliness, smiling can benefit healthcare ...