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Now showing items 3102-3121 of 3493
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Takotsubo cardiomyopathy secondary to elective sclerotherapy for varicose veins
(BMJ, 2022-07-04)A man in his 70s presented to the emergency department with ongoing chest pain, which started directly after receiving sclerotherapy for the treatment of varicose veins. This was on a background of experiencing short-term ... -
Tape to view: novel technique to improve axillary access
(Royal College of Surgeons of England, 2019-11) -
Target inhibition of galectin-3 by inhaled TD139 in patients with idiopathic pulmonary fibrosis
(HighWire, 2021-05-27)Galectin (Gal)-3 is a profibrotic β-galactoside-binding lectin that plays a key role in the pathogenesis of idiopathic pulmonary fibrosis (IPF) and IPF exacerbations. TD139 is a novel and potent small-molecule inhibitor ... -
Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: results from the initial screening round of the IMPACT study
(Elsevier, 2014-09-01)BACKGROUND: Men with germline breast cancer 1, early onset (BRCA1) or breast cancer 2, early onset (BRCA2) gene mutations have a higher risk of developing prostate cancer (PCa) than noncarriers. IMPACT (Identification of ... -
Targeting surface voids to counter membrane disorders in lipointoxication-related diseases.
(The Company of Biologists, 2016-06-15)Saturated fatty acids (SFA), which are abundant in the so-called western diet, have been shown to efficiently incorporate within membrane phospholipids and therefore impact on organelle integrity and function in many cell ... -
The Tatton-Brown-Rahman Syndrome: A clinical study of 55 individuals with de novo constitutive DNMT3A variants
(Wellcome, 2018-04)Tatton-Brown-Rahman syndrome (TBRS; OMIM 615879), also known as the DNMT3A-overgrowth syndrome, is an overgrowth intellectual disability syndrome first described in 2014 with a report of 13 individuals with constitutive ... -
Teaching classroom management ? a potential public health intervention?
(Emerald, 2015-06)The purpose of this paper is to explore the feasibility of a classroom management course as a public health intervention. Improved socio-emotional skills may boost children’s developmental and academic trajectory, while ... -
A technique to visualise the urethral meatus in difficult male catheterisations.
(Royal College of Surgeons, 2015-12-16) -
Telephone clinics for follow-up in hand surgery: an effective model after COVID-19?
(Royal College of Surgeons, 2021-07-01)IntroductionTelephone clinics were adopted for follow-up appointments in our plastic hand surgery department during the COVID-19 pandemic. They may pose advantages in cost, efficiency and environmental impact compared wi ... -
Telephone Interview for Cognitive Status Scores Associate with Cognitive Impairment and Alzheimer's Disease Pathology at Death
(IOS Press, 2021-11-09)BACKGROUND: Early diagnosis of Alzheimer's disease (AD) provides an opportunity for early intervention. Cognitive testing has proven to be a reliable way to identify individuals who may be at risk of AD. The Telephone ... -
Telerehabilitation for people with physical disabilities and movement impairment: development and evaluation of an online toolkit for practitioners and patients
(Taylor & Francis, 2022-05-22)PURPOSE: Telerehabilitation has increasingly been used since the COVID-19 pandemic but with limited guidance available on undertaking physical assessments using remote methods. We aimed to provide such guidance by developing ... -
Telerehabilitation for physical disabilities and movement impairment: A service evaluation in South West England
(Wiley, 2022-04-19)RATIONALE, AIMS AND OBJECTIVES: Telerehabilitation was used to ensure continued provision of care during the COVID-19 pandemic, but there was a lack of guidance on how to use it safely and effectively for people with ... -
Telomere length and aging-related outcomes in humans: A Mendelian randomization study in 261,000 older participants
(Wiley, 2019-12)Inherited genetic variation influencing leukocyte telomere length provides a natural experiment for testing associations with health outcomes, more robust to confounding and reverse causation than observational studies. ... -
Telomere length and risk of idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease: a mendelian randomisation study
(Elsevier Science, 2021-03)Background: Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease accounting for 1% of UK deaths. In the familial form of pulmonary fibrosis, causal genes have been identified in about 30% of cases, and a majority ... -
Temperature Spatially Offset Raman Spectroscopy (T-SORS): Subsurface Chemically Specific Measurement of Temperature in Turbid Media Using Anti-Stokes Spatially Offset Raman Spectroscopy.
(American Chemical Society, 2016-01-05)Here we propose and demonstrate a new analytical method for the noninvasive measurement of subsurface temperatures within diffusely scattering (turbid) media in combination with high chemical selectivity. The method is ... -
Temporal Relationship Between Depressive Symptoms and Cognition in Mid and Late Life: A Longitudinal Cohort Study
(Elsevier Science, 2020-08)Objectives: To examine the bidirectional temporal relationship between depressive symptoms and cognition in relation to risk, reaction, and prodrome. Design: Cross-lag analysis of longitudinal data collected online at ... -
Ten areas for ICU clinicians to be aware of to help retain nurses in the ICU
(BioMed Central, 2022-10-13)Shortage of nurses on the ICU is not a new phenomenon, but has been exacerbated by the COVID-19 pandemic. The underlying reasons are relatively well-recognized, and include excessive workload, moral distress, and perception ... -
Ten years of the national genetic diabetes nurse network: a model for the translation of genetic information into clinical care
(Clinical Medicine, 2014-04-01)Increasing technological advances have resulted in the recognition of a range of genetic conditions not traditionally seen by clinical genetics teams. This has implications for the education of other healthcare professionals ... -
Ten-year results for a single-surgeon series of Scorpio non-restrictive geometry (NRG) posterior stabilised (PS) total knee replacement
(Springer, 2019-05)To report the long-term results for a single-surgeon consecutive series of Scorpio non-restrictive geometry (NRG) posterior stabilised (PS) total knee replacement (TKR).