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Now showing items 331-350 of 3493
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Babies of South Asian and European Ancestry Show Similar Associations with Genetic Risk Score for Birth Weight Despite the Smaller Size of South Asian Newborns
(American Diabetes Association, 2022-01-21)Size at birth is known to be influenced by various fetal and maternal factors including genetic effects. South Asians have a high burden of low birthweight and cardiometabolic diseases, yet studies of common genetic ... -
Back to the gallstone: a mischievous cause of morbidity.
(BMJ, 2016-06-17)Laparoscopic cholecystectomies (LCs) are the gold standard treatment of symptomatic gallstone disease worldwide. However, with this technique comes the increased risk of retained spilled gallstones. We describe a case of ... -
Baraitser-Winter Cerebrofrontofacial Syndrome.
(Wiley, 2016-09-13)Baraitser-Winter Cerebrofrontofacial syndrome (BWCFF) [BRWS; MIM #243310, 614583] is a rare developmental disorder affecting multiple organ systems. It is characterised by intellectual disability (mild to severe) and ... -
Barriers and facilitators to clinical behaviour change by primary care practitioners: a theory-informed systematic review of reviews using the Theoretical Domains Framework and Behaviour Change Wheel
(BioMed Central, 2022-08-30)BACKGROUND: Understanding the barriers and facilitators to behaviour change by primary care practitioners (PCPs) is vital to inform the design and implementation of successful Behaviour Change Interventions (BCIs), embed ... -
Barriers to undertaking technical skills
(Wiley, 2020-04) -
Bayesian analysis of glomerular filtration rate trajectories in kidney transplant recipients: a pilot study
(Transplantation, 2015-03-01)BACKGROUND: Detailed modeling and analysis of renal (dys)function trajectories has not been undertaken in kidney transplant recipients. Although previous studies have assumed linear trajectories, this likely represents an ... -
BBS5 and INPP5E mutations associated with ciliopathy disorders in families from Pakistan
(Wiley, 2019-11)Ciliopathies are a clinically and genetically heterogeneous group of disorders often exhibiting phenotypic overlap and caused by abnormalities in the structure or function of cellular cilia. As such, a precise molecular ... -
BCL11A Haploinsufficiency Causes an Intellectual Disability Syndrome and Dysregulates Transcription
(Elsevier, 2016-07-21)Intellectual disability (ID) is a common condition with considerable genetic heterogeneity. Next-generation sequencing of large cohorts has identified an increasing number of genes implicated in ID, but their roles in ... -
Behavioural changes in the rat following infection with varicella-zoster virus
(Microbiology Society, 1999-09-01)Following the establishment of a chronic varicella-zoster virus infection in the rat, behavioural allodynia and hyperalgesia were observed in the injected, but not the contralateral hind limb up to 33 days post-infection. ... -
Being and becoming a spasticity nurse specialist: a reflexive narrative study
(Mark Allen Group, 2015-06-02)Spasticity is a common neurological symptom that can lead to complex disability, particularly in progressive multiple sclerosis (MS). A key role of the specialist spasticity nurse is to support people to effectively manage ... -
Benefits and harms of electrical neuromodulation for chronic pelvic pain: a systematic review
(Elsevier, 2019-10)Patients with chronic pelvic pain (CPP) may have pain refractory to conventional pain management strategies. Neuromodulation could provide relief of pain. -
Benign Prostatic Hyperplasia
(StatPearls Publishing, 2020-01)Benign prostatic hyperplasia (BPH) refers to the nonmalignant growth or hyperplasia of prostate tissue and is a common cause of lower urinary tract symptoms in men. Disease prevalence has been shown to increase with advancing ... -
BESS Abstracts
(Sage, 2016-09-08) -
Beta cell function and ongoing autoimmunity in long-standing, childhood onset type 1 diabetes.
(Springer, 2016-09-03)This study aimed to determine the frequency of residual beta cell function in individuals with long-standing type 1 diabetes who were recruited at diagnosis, and relate this to baseline and current islet autoantibody profile. -
Beta cells in type 1 diabetes: mass and function; sleeping or dead?
(Springer, 2019-04)Histological analysis of donor pancreases coupled with measurement of serum C-peptide in clinical cohorts has challenged the idea that all beta cells are eventually destroyed in type 1 diabetes. These findings have raised ... -
Beta human papillomaviruses infection and skin carcinogenesis
(Wiley, 2020-07)During the last decade, the worldwide incidence of keratinocyte carcinomas (KC) has increased significantly. They are now the most common malignancy, representing approximately 30% of all cancers. The role of ultraviolet ... -
Beta-blockers in liver cirrhosis
(Hellenic Society of Gastroenterology, 2014-01-01)Since the original description of the effectiveness of beta-blockers in lowering the portal pressure and therefore the risk of variceal bleeding, more than 500 articles in the English literature on the use of non selective ... -
Beta-cell dysfunction, insulin sensitivity, and glycosuria precede diabetes in hepatocyte nuclear factor-1alpha mutation carriers.
(Highwire, 2005-07)Patients with diabetes due to hepatocyte nuclear factor (HNF)-1alpha mutations have beta-cell deficiency, insulin sensitivity, altered proinsulin levels, and a low renal threshold for glucose. It is uncertain how many of ... -
beta-cell genes and diabetes: molecular and clinical characterization of mutations in transcription factors.
(Highwire, 2001-02)beta-Cell transcription factor genes are important in the pathophysiology of the beta-cell, with mutations in hepatocyte nuclear factor (HNF)-1alpha, HNF-4alpha, insulin promoter factor (IPF)-1, HNF-1beta, and NeuroD1/BETA2, ...