Welcome to the RD&E Research Repository
The RD&E Research Repository contains research outputs from staff at the Royal Devon & Exeter NHS Foundation Trust.
You can browse items by Title, Author, Subject or Community/Collection, or use the search function to find specific topics.
The repository contains details of published, peer-reviewed journal articles, reviews, book chapters, conference abstracts, posters and more! Full-text of journal articles have been included where publisher's permissions allow.
If you are a member of RD&E staff and you'd like to submit an item to the repository, please fill in this online form. If you have a list of publications you'd like to submit, please e-mail the repository admin team: rde-tr.ResearchRepository@nhs.net.
For more information or help, please contact the RD&E Research Repository admin team:
Telephone: Exeter Health Library, 01392 406800
Communities in RD&E Research Repository
Select a community to browse its collections.
A Non-Coding Disease Modifier of Pancreatic Agenesis Identified by Genetic Correction in a Patient-Derived iPSC Line (Elsevier Science, 2020-07-02)GATA6 is a critical regulator of pancreatic development, with heterozygous mutations in this transcription factor being the most common cause of pancreatic agenesis. To study the variability in disease phenotype among ...
(Elsevier Science, 2020-10)Purpose: To describe patients with late-onset pseudoxanthoma elasticum (PXE) associated with a likely hypomorphic ABCC6 variant. Design: Retrospective observational case series. Methods: Clinical evaluation, multimodal ...
An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells (Nature Publishing Group, 2-05-22)Interferon-α (IFNα), a type I interferon, is expressed in the islets of type 1 diabetic individuals, and its expression and signaling are regulated by T1D genetic risk variants and viral infections associated with T1D. We ...
Risk factors for genital infections in people initiating SGLT2 inhibitors and their impact on discontinuation (BMJ, 2020-05)Introduction: To identify risk factors, absolute risk, and impact on treatment discontinuation of genital infections with sodium-glucose co-transporter-2 inhibitors (SGLT2i). Research design and methods: We assessed the ...
Primary care faecal calprotectin testing in children with suspected inflammatory bowel disease: a diagnostic accuracy study (BMJ, 2020-10)Objective: To determine the diagnostic accuracy of calprotectin to diagnose inflammatory bowel disease (IBD) in children in whom general practitioners (GPs) suspected IBD. Design: Prospective observational cohort study ...